Pulpitis often requires endodontic treatment, but options like pulpotomy with calcium-silicate cements offer promising alternatives. In a 9-year-old with irreversible pulpitis in a mandibular molar, complete coronal pulpotomy with Biodentine were applied. After 6 months of follow-up, the patient remained symptom-free, with no signs of inflammation or infection in the treated tooth. Another case of pulpotomy done in young permanent anterior teeth with 12 month follow up which showed progressive root development and another case of primary teeth is also illustrated in this case series which describes the clinical effectiveness of Biodenine in vital pulp procedures.