The article reveals current social problems of improving people's health by replacing chemical plant protection products (pesticides) with environmentally friendly and safe biological agents in the biocontrol of diseases and pests of vegetable crops and potatoes. The prospects for using extremophilic soil bacteria of the genus Bacillus in the biocontrol of potato diseases are determined. As a result of the research, Bacillus sp. RT-3 and Bacillus sp. RT-6 extremophilic bacteria showed high antagonistic activity against phytopathogens Phytophtora infestans, Fusarium oxysporum f. sp. lycopersici, Fusarium solani, Alternaria solani, Alternaria alternata and Rhizoctonia solani.