The element of the human body responsible for coordinating behaviour and sending messages between various bodily parts is the nervous system. The trigeminal (V) nerve, which supplies facial expressions and aids in mastication, swallowing, and breathing, is part of the extensive sensory and motor nerve network that supplies the orofacial region. Trigeminal nerves' sensory and motor distributions are closely related to each other anatomically and functionally. Before creating a prosthesis for a patient, a complete understanding of these nerves, their lesions, and their therapy is necessary. Neurological lesions or injuries to these nerves impact natural expressions.