Sex work remains a contentious issue globally, with significant implications for public health, particularly concerning the spread of sexually transmitted diseases (STDs). In India, where STDs rank among the top communicable diseases, addressing the health needs of sex workers is paramount. This paper advocates for a reform in sex worker policy as a crucial step in combating STDs and safeguarding public health. By examining the complex intersection of sex work, STDs, and public health in India, this paper highlights the urgent need for comprehensive strategies that prioritize the health and rights of sex workers. Drawing on evidence-based approaches and emphasizing the importance of destigmatization, empowerment, and access to healthcare services, this paper underscores the imperative for policy reform to effectively address the challenges posed by STDs among sex workers in India.