Background Congenital heart diseases (CHDs) are considered as the most common congenital birth defects, comprising 1% of all live births. Multi-detector computed tomography (MDCT) can show the morphology of extra-cardiac vasculature, including the coronaries, pulmonary arteries, aorta, and pulmonary or systemic veins, and it delineates vessel walls and also displays the airway, mediastinal abnormalities, and pulmonary parenchyma. AIMS The aim of the study is to study different findings in various cardiovascular anomalies in patients with congenital cyanotic heart disease by MDCT, find out relative distribution of various congenital cyanotic heart disease and their morphological component and to obtain role of MDCT in obtaining additional information in pre-operative patients, inconclusive on echocardiography. Material/Methods This Prospective study was conducted at The B. J. Medical College, Ahmedabad. A total of 100 patients were included in the study aged between 1 day to 15 years. All patients were referred by cardiologists in the period from 1st October 2017 to 15th November 2019 to perform CT angiography examination. All images included axial, MPR, MIP, and VRT and were interpreted in one session. Pulmonary veins were assessed for PAPVR or TAPVR, PDA, cardiac apex and heart chambers, interatrial or interventricular septal defects, pericardium, and site and size of the great veins (IVC and SVC). Results This study included 100 patients. Congenital cyanotic heart diseases are found more in males-56 males (56%) and 44 females (44%) with the ratio of M: F being 1.27:1. The cyanotic heart diseases are more prevalent in less than 01-year age with the number of cases being 53 (53%).. The study reveals that situs solitus is seen in 93 (93%) cases, situs inversus in 1 (1%) cases and situs ambiguous in 6 cases (6%). Tetralogy of Fallot and double outlet right ventricle are the most common cyanotic heart diseases. Overall 277 cardiovascular malformations were identified in this study of 100 patients on MSCT angiography. Conclusions MDCT proved to be an important modality for decision-making in patients with congenital cyanotic heart diseases.