Volume 7 | Issue - 1 articles in press
Volume 7 | Issue - 1 articles in press
Volume 7 | Issue - 1 articles in press
Volume 7 | Issue - 1 articles in press
Volume 7 | Issue - 1 articles in press
Designing a highly effective class of innovative antimicrobial agents poses a significant challenge in the field of pharmaceutical research and development. The ongoing research focuses on discovering a new series of quinazoline and its derivatives with various substitutions. The synthetic process involves a couple of steps to prepare the quinazoline compound by reacting an amphoteric aromatic acid like Anthranilic acid the desired chlorine compound Benzoyl chloride in presence of highly flammable, weakly alkaline, heterocyclic organic compound Pyridine, resulting in the formation of 2-phenyl-benzoxazine-4-one which is an intermediate compound which is further allowed to react with the hydrazine hydrate along with the pyridine and upon reflux for 3 hours will yield the desired quinazoline compound 3-Amino-2-phenyl-quinazoline-4-one. All the synthesized compounds undergo characterization use. Techniques such as IR spectroscopy, Proton nuclear magnetic resonance (1HNMR), Carbon 13C NMR , Mass spectral methods. Furthermore, these compounds are screened for their antimicrobial activity against bacterial strains such as E. coli, Pseudomonas aeruginosa, Bacillus subtilis, and fungal strains like Aspergillus, and candida albicans.