ISSN : 2663-2187

Synthesis and Molecular Docking of Novel 1,3-oxazole and 1,3- thiazole Derivatives of Ciprofloxacin for their Anticancer Activity

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Rafid M. Hashim, Zainab Haithem Kadhim, Ranen Hashim Rida
ยป doi: 10.33472/AFJBS.6.8.2024.1392-1399

Abstract

In this study, cioprofloxacin served as the starting point for the preparation of the new compounds. It underwent a ring expansion to form 1,3-oxazole and 1,3-thiazole, both of which have five atoms. First, ciprofloxacin was reacted with thionylchloride and absolute ethanol to produce compound [2].

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