Background: Prostate cancer (PC) is the fifth most common cancer in the world, being the second most frequent among men, behind only non melanoma skin cancer. Its incidence has been higher in developed countries compared to less developed countries, being more common in men over 50 with the risk increasing with advancing age, with approximately 75% of cases in elderly people over 80 years. The main methods of screening for PC are digital rectal examination, sextant prostate biopsy and prostate-specific antigen (PSA). Its levels can be influenced by prostatic changes and non-malignant changes (age, use of drugs, inflammation of the prostate, race/ethnicity, weight, body mass index (BMI), obesity and diabetes). The aim: The aim of this study to show about association of sedentary lifestyle and prostate specific antigen.