ISSN : 2663-2187

The Effect of Loperamide on Pain Intensity and IL-6 Levels in Patients Undergoing Hysterectomy With Spinal Anesthesia

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Luthfi Afiat, Nur Surya Wirawan, Muh. Ramli Ahmad, Andi Husni Tanra, Alamsyah Ambo Ala, Charles Tan
» doi: 10.48047/AFJBS.6.14.2024.960-968

Abstract

Background:Hysterectomy is the most common gynecological surgical procedure performed in various countries. Spinal anesthesia has become a popular technique for surgery on the lower abdomen, pelvis, and lower extremities. Loperamide, an opioidergic drug used to treat non-bacterial diarrhea by decreasing intestinal motility and has been reported to produce analgesic effects. However, research related to the effect of loperamide use on IL-6 levels after surgery has never been conducted before.

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