Acer tegmentosum Maxim is a deciduous hardwood tree known for its therapeutic effects in conditions such as liver cancer, hepatocirrhosis, hepatitis, and leukemia. The leaves of Acer tegmentosum Maxim are rich in potassium, contributing to its effectiveness in preventing and treating hypertension. Acer tegmentosum Maxim extract possesses anti-angiogenic, antiinflammatory, and antioxidant properties. Studies suggest potential roles in reducing neutral fats and total cholesterol, as well as acting as a plant-based estrogen. This research explores the correlation between inhalation of Acer tegmentosum Maxim extract and cerebral blood flow. Despite improved information accessibility in modern society, stress levels and mental health issues continue to rise. Humanistic therapy, a form of mental care utilizing the humanities for self-insight and transformation, was applied to science and engineering students alongside the examination of cerebral blood flow changes using transcranial Doppler ultrasound. The results indicate an increase in mean blood flow velocity in the posterior cerebral artery (PCA) and internal carotid artery (ICA) after inhaling Acer tegmentosum Maxim extract, suggesting potential associations with cognitive function and cerebral blood flow.