Historically, the environmental resources, especially the river were recognized as limitless and primarily known to harbour plentiful fish species. The frequent and overuse of various pesticides and chemical elements including the fertiliser for agriculture needs may instigate several environmental damage. In this regard, here the author has investigated the possible role of the ammonium phosphate sulphate in Pseudetroplus maculatus in context with toxicological and environmental inferences. One-way ANOVA, paired test, cross tab-analysis and Correlation were used to unveil the possible link between the Pseudetroplus maculatus and the ammonium phosphate sulphate.