Herpes zoster is characterized by the appearance of clustered blistering lesions in a specific area of the skin. While this is the typical presentation, there are also rare cases that involve multiple dermatomes or affect internal organs. In this report, we discuss three uncommon cases of herpes zoster with atypical presentations. Case series: The first case was a patient with herpes zoster oticus, also known as Ramsay Hunt syndrome, which manifested with facial nerve palsy. The second case exhibited vesicles in two separate dermatomes on both sides of the body, a condition referred to as herpes zoster duplex bilateralis. The third case presented with painful blisters in the sacral dermatome, an unusual location, along with urinary symptoms. Conclusion: People of elderly age and immunocompromised persons are at risk of developing such atypical manifestations of herpes zoster It is crucial for clinicians to recognize these atypical manifestations of herpes zoster and promptly initiate treatment to prevent potential complications and morbidity