Using biotechnology, substantial amounts of mechanization, and significant energy inputs in the form of enhanced irrigation, fertilizers, and pesticides, modern agriculture is a sophisticated scientific endeavor. The application of pesticides and fertilizers has resulted in a notable boost in our agricultural output. The development of these synthetic materials involves a significant amount of chemistry and the chemical industry. In the last several decades, many inorganic and organic substances have been created and evaluated for use as agrochemicals. Regarded as an inorganic nutrient source, chemical fertilizers are essential for both sustaining soil productivity and raising crop yields. For the last 35 years, 50–55% of the increase in yield in developing countries can be attributed to the nutrients provided by synthetic fertilizers. Even though inorganic fertilizers have grown in popularity in India in recent years, the country's fertilizer nutrient use efficiency remains low (30–50% for N and 15-20% for P), which is the cause of nutrient losses or their conversion into slowly cycling in the soil. The fertilizer business is always trying to find ways to make its products better so that they may be used more effectively— especially when it comes to nitrogenous fertilizers—and have minimal negative influence on the environment as possible. This is accomplished either by creating new, targeted fertilizer kinds or by improving the fertilizers that are currently in use. Over time, the use of high-analysis fertilizers, such as urea instead of ammonium sulfate and diammonium phosphate in place of regular superphosphate, has resulted in a significant decline in the application of sulfur to crop fields, which has caused a widespread sulfur deficit in Indian soils. sulfur (S) and increased fertilizer nitrogen efficiency. Applying 100% NCU, 100% NCU, and 100% N urea combined with 100% P K increased grain yield by 59%, 57.8%, and 41.5%, respectively. This is known as coated urea. Significantly more wheat grain was produced than with the control treatment, even with 75% N via SCU and full dosages of P and K. The recommendation is to use sulfur and improve the efficiency of nitrogen fertilizer for wheat in India, as it meets the needs of the wheat crop and increases nitrogen recovery efficiency by 60%.