Cancer may be regarded as a group of diseases characterized by abnormal growth of cells, ability invade adjacent tissues and even distant organs and the eventual death of the affected patient if the tumor has progressed beyond that stage when it can be successfully removed.1 Cancer is becoming an increasingly important factor in the global burden of disease in the decades to come.The estimated number of new cases each year is expected to rise from 10 million in 2000 to 15 million by 2020. Some 60% of all these new cases will occur in the less developed parts of the world.2 Keeping this in view, the present study was conducted to assess the health profile and warning signs of cancer among adults residing in selected rural community areas of Nellore, Andhra Pradesh. The aim of the study was to assess the health profile of adults residing in selected rural areas of Nellore District. Andhra Pradesh. The objectives are 1. To assess the Health Profile and warning signs of cancer among adults. 2. To determine the association between Health Profile and warning signs of cancer with the selected socio- demographic variables among adults. Total 200 adults were selected by convenience sampling technique. Sociodemographic sheet, health profile sheet and warning signs of cancer assessment sheet were used to collect data to assess the health profile and warning signs of cancer among adults. Content validity of the tool was obtained from the experts. Reliability of the tools was calculated by split half method and tools found reliable. Descriptive and inferential statistics were used for data analysis. The result revealed that there is no warning signs of cancer were present among adults. 28 (14 %) of adults had constipation and 22 (11 %) of the subjects had indigestion. The study concluded that there is a need of health education regarding early identification of cancer with warning signs of cancer.