INTRODUCTION: Carcinoma is basically the rapid production of unhealthy cells that are not controllable. Individuals receiving anti-cancer meds generate a feeling of being sick for days together. Nausea and vomiting greatly being the commonest effect cause alterations in patients’ health by decreasing nutritional state, exhausting the metabolism which results in constipation. Nevertheless, antiemetics can be administered to obviate emesis during cancer therapy. In this study, we have assessed the level of chemotherapy induced nausea and vomiting. MATERIALS AND METHODS: 60 patients were assessed for the level of chemotherapy induced nausea and vomiting by using purposive sampling technique. Using 7-point semantic differential rating scale assessment was done in first 24 hours. RESULTS: From 60 patients assessed8 (50%), Govt-Employeehad mild level of chemotherapy induced nausea and vomiting with chi-square (15.589) and p value 0.049 and 41.67% had mild nausea, 33.33% had moderate nausea, 25.00% of them had severe. CONCLUSION: The present study observed the level of nausea and vomiting, the interconnection between chemotherapy induced nausea and vomiting and selected demographic variables of patient with cancer showed that occupation is having a significant relationship with chemotherapy induced nausea and vomiting.