Salmonella enterica belongs to the gram-negative, rod-shaped anaerobic bacteria family called Salmonellae. Salmonellosis infections can be foodborne, non-food-borne transmission between animals and between humans and animals. Pathology of salmonella enterica is influenced by the type of host population including the risk group like elderly, children and immunocompromised patients, virulence and colonization factor of the organism. Abdominal discomfort, bloody or non-bloody diarrhoea, nausea, and vomiting are all of the disease's primary symptoms, and they can cause systemic, non-intestinal, and intestinal complications. Routine antimicrobial therapy is not advised for mild or moderate infections in healthy persons.