ISSN : 2663-2187

A STUDY ON AN IN-VITRO UROLITHIATIC ACTIVITY OF AQUEOUS EXTRACTS OF LEAVES OF TECOMA STANS

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Geetha Rani Valaparla, B.Mythri, Y.Ujwala, L.Nagalakshmi, J.Srinivas, N.Ganesh, M.Ravali
» doi: 10.48047/AFJBS.6.12.2024.4852-4857

Abstract

Kidney stones, also referred to as renal calculi, are hard solid structures formed from crystal substances. These stones usually start in your kidneys but can form at any point along the urinary system. When looking at the likelihood of recurring stones, it's anywhere from 21% to 53% within three to five years after the initial occurrence. The study observed the occurrence of urolithiasis, which is the formation of urinary stones, ranges from 5% to as high as 19.1% across West Asia, Southeast Asia, South Asia, and certain industrialized nations like South Korea and Japan, compared to a lower incidence of 1% to 8% in the majority of East Asia and North Asia. Commercially so many drugs are available for this treatment.But the natural remedies are known to have a lower risk of causing less adverse effects or allergic reactions compared to other treatments. The aim of the present study is to evaluate the urolithiatic activity of the leaves of tecoma stans.Thiscan be done by carrying out pharmacological studies with the aqueous leaves extract in-vitro models with the use of Semi-Permeable Membrane from Farm Eggs. The percentage dissolution of stones, observed in each group: the positive control yielding a 95% dissolution, the negative control at 20%, the high dose of Tecoma stans demonstrating an89% dissolution, and the low dose of Tecoma stans at 65%. The findings of the Present investigation suggests that Tecoma stans has anti urolithiatic activity.

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