Introduction: The play is a universal language for children. Play allows children to learn social behaviours, develop cognitive abilities as well as gross motor skills, and work through emotional conflicts. Play therapy is very effective for revisiting traumatic memories in order to get a child familiar with fear and anxiety. Children between 6 and 12 years old will begin valuing friendships and becoming more involved in activities like drawing, games, sports and/or painting. Anxiety due to hospitalizations can affect children’s mental growth, physical growth, as well as personality development. Aim: To reduce the anxiety of the school aged hospitalized children at selected hospital of Anand district. Method: A Convergent mixed method approach was used for the study. 50 school aged hospitalized children were selected using non- convenient sampling technique and divided equally in two groups interventional group and control group. The play activity was provided for once a day for consequently 3 days for 20-30 minutes at selected hospital of Anand district. The socio demographic data was collected the using self-structured tool and level of anxiety was assessed using self-structured questionnaire before intervention in experimental and control group. On day 3rd post-test was taken in both interventional and control group. In interventional group anxiety was assessed through self-structured anxiety questionnaire and one to one opinion of the child’s care giver. Result: An Independent t-test was used to assess the level of anxiety and score was (t=7.593), level of distress Anxiety score (t=5.081) was found to be significant at 0.000 level. So, there is significant difference in the level of anxiety in school aged hospitalized children after the play activity in interventional group (P<0.05). There was no significant association between sociodemographic variables in level of anxiety (p>0.05).Conclusion: School-aged hospitalized children are more anxious; therefore, minimize their anxiety by providing various forms of play activities for children. Play was useful in reducing the anxiety of school-aged hospitalized children. It can also be provided by a child's care giver during hospitalization to help reduce anxiety.