Background and objectives: Acute lymphoblastic leukemia is among the common hematological malignancies in adults and constitutes 20% of adult malignancies. This research aimed to study sociodemographic and laboratory diagnostic results in adults with acute lymphoblastic leukemia recorded in Hiwa Cancer Hospital. Methods: This retrospective cross-sectional study included 100 adult patients with acute lymphoblastic leukemia (≥18 years old) recorded in Hiwa Cancer Hospital, from April 2015 to August 2023. A standard spreadsheet was used for each patient's sociodemographic data and diagnostic findings, including complete blood count, bone marrow blast count, immunophenotyping, and genetic mutation. Results: Most leukemic patients had B-cell acute lymphoblastic leukemia (74%), were aged (18-30) years (47.0%), were males (71%), had healthy weight (41%), and had O+ blood group (36%). Only 10 (14.7%) patients had positive BCR-ABL gene mutation (7.0 for protein 190 and 3.0 for protein 210). There was a significant correlation (p≤0.05) between both subtypes (B-ALL, T-ALL) regarding age. In contrast, no significant associations were detected for gender, body mass index, blood group distribution, and season of diagnosis (p≥0.05) among patients. Regarding the blood parameters, the mean leukocytes and platelets in the B-subtype patients were significantly (p≤0.05) lower than T-subtypes. In contrast, no significant association (p≥0.05) in the mean hemoglobin and bone marrow blast levels was seen between both subtypes. Conclusions: B-subtype is more common in our locality and is related to age but not to gender, body mass index, blood group, and season of diagnosis.