Allelochemicals are subsets of secondary metabolites that no longer required for metabolism of the allelopathic organism and their poor allelopathic results are vital part of organism defense against antagonists. Allelopathic interactions involving Cyanobacterial flora are being explored for their pharmaceutical and environmental importance. Cyanobacterial allelopathy may be appeared as one of the massive elements influencing their dominance in numerous habitats and as particular producers of a selection of allelochemicals that can be applied as green biocontrol marketers. In present work detrimental (dreadful allelopathy) effects of locally isolated Cyanobacterial strains had been evaluated in opposition to plant pathogenic three fungal isolates ( Fusarium oxysporum, Sclerotium rolfsi and Rhizoctonia solani). It turned into discovered that the crude extracts of 4 Cyanobacterial isolates (Microcystis aeruginosa, Oscilatoria boryana, Anabaena sphaerica and Nostoc calcicola), had been able to diminishing the boom and similarly development of phyto-pathogenic fungal isolates. While M. Aeruginosa showed greater allelopathic interest compared to different cyanobacterial strains. Methanol crude extracts have been extra efficient. Crude extract (100 % in Methanol) of Microcystis aeruginosa changed into determined extra efficient towards neighborhood isolates Fusarium oxysporum (% MI – 88.Forty six ± 0.24) and Sclerotium rolfsii (83.42), in comparison to Rhizoctonia solani (78.33). Allelopathic potentiality of cyanobacteria have need to be further investigated which could provide promising answers in bio-control in opposition to pathogenic Fungi.