ISSN : 2663-2187

Alpha-amylase inhibitory activity and phytochemical study of Anabasis articulata

Main Article Content

Sousen Labiodh , Firial Mahfoudi , Rokia Mahfoudi
» doi: 10.48047/AFJBS.6.15.2024.9575-9581

Abstract

This work aims to contribute to the phytochemical study of the plant(Anabasis articulata) and to estimate the inhibitory efficacy of the alpha-amylase enzyme for its extracts. Through initial tests it was found that most ofthe products of secondary metabolism, especially flavonoids and alkaloids, wereextracted by four different polar solvents (distilled water, Methanol, hexane andacetone), where we obtained the highest yield in the aqueous extract (2.53%),and all the extracts were subjected to a quantitative analysis of phenolic,flavonoids and tannins, as we found that the largest amount of phenols in theaqueous phase (1251.77 mg equivalent for gallic acid / 100 g of dry matter( forflavonoids and tannins in methanol extract (44.38 mg equivalent to christin / 100g for dry matter and 755.17 mg equivalent for catechin / 100 g of dry matter) respectively.We also studied the inhibitory efficacy of the alpha-amylase enzyme forall extracts, so the aqueous extract efficacy was optimal, followed by themethanol extract (585.02 and 83.93 mg acarbose equivalent / 100 g of drymatter), respectively, because they contained the largest amount of total phenolsin addition to flavonoids, Which was responsible for inhibition, and this allowedthe plant to be used as an alternative treatment for diabetics.

Article Details