Doxazosin is an alpha blocker. It works to relax certain muscles in your body. It is a quinazoline derivative that acts as a competitive alpha1 antagonist at the post-synaptic receptor. It relaxes your veins and arteries so that blood can more easily pass through them. It also relaxes the muscles in the prostate and bladder neck, making it easier to urinate. Aim and Objective: An Experimental Study to Evaluate the Analgesic and Anxiolytic Effects of Doxazosin in Swiss Albino Mice Material and Methods: The study was carried out in the Department of Pharmacology & Therapeutics at King George’s Medical University, Lucknow. The present study was designed to evaluate antianxiety and analgesic effect of doxazosin in an experimental model in swiss albino mice. A total number of 36 female Swiss albino mice were included in the study. They were kept in the institutional animal house under standard conditions. They received normal pellet diet and water ad libitum. They were allowed to get acclimatized to the new environment for a period of 2 weeks. Mice were randomly divided into 3 groups for each parameter, each group containing 6 mice.