Background: A rise in blood creatinine or a decrease in urine volume are symptoms of (AKI), which is a sudden and frequently reversible loss of kidney function. Kidney Disease Improving Global Outcomes (KDIGO) provided an updated definition, which is currently the most widely used. According to KDIGO, CI-AKI is defined as a creatinine level increase of ≥ 0.3 mg/dl (26.5 μmol/l) above baseline value within 48 h of contrast media exposure, or an increase of at least 1.5 times the baseline value within 7 days. Contrast induced nephropathy (CIN) is defined as acute renal impairment after exposure to iodinated contrast media (CM). In the modern era with the advancement of the diagnostic modalities, increase in number of percutaneous coronary and peripheral artery interventions and frequent use of contrast media, CIN has emerged as a common cause of acute renal failure. Mostly, it results in transient renal impairment; however in patients with multiple comorbidities it can be associated with high morbidity and mortality. It is therefore imperative to identify patients at risk to decrease its occurrence and diagnose it early in course to avoid short and long term clinical adverse effects. It presents a challenging situation that is often encountered by practitioners in varied specialties including emergency medicine, nephrology, cardiology, radiology and intensive care unit (ICU). Currently, contrast-associated acute kidney injury (CA-AKI) is a common cause of hospital-acquired AKI in the older patients