This study reports the Method Development and Validation For Anti Diabetic Drugs By Rp-Hplc. The drug analysis is playing an vital position within the improvement of medicine, their manufacture and therapeutic use For the simultaneous estimation of medicine present in dosage forms, lot, of suitable techniques are adopted like uv – spectrophotometer HPLC. Those techniques are powerful rugged technique .they're additionally extraordinarily specific, specific, correct, linear and speedy. A pharmaceutical industry depends upon quantitative chemical analysis to make sure that the raw material used and the final product obtained meets the required specification. The drugs will occur as a unmarried factor or multi issue dosage paperwork. The later proves to be effective because of its mixed mode of movement at the body.