Introduction: Apiarian products like royal jelly and propolis have gained significant attention in biomedical research due to their diverse chemical composition and reported health benefits.According to literature there have not been enough proven uses of Royal jelly and Propolis in dental studies. Material and Methods: Preparation of test substances was done. Zebra fish was maintained and acclimatised.Experimental groups were divided into 3 with Group A:Control group , Group B;Propolis 155 15mg/ml and Group C:Royal jelly 15% 15mg/ml.All the three groups were observed and assessed by monitoring cytotoxicity with 3 parameters a) Survival rate b)Hatching rate c)Heart rate.Data were collected and given as the mean+_ standard deviation (SD) of triplicates. GraphPad Prism (ver 5.0) was used to do one way ANOVA followed by Tukey Multiple Range Test, with statistical significance levels set at p< 0.05 and p< 0.01Results: Survival rate was seen higher for Propolis 15% followed by Royal jelly 15% and then the calcium hydroxide when compared with the control group.Hatching rate was seen higher for royal jelly 15% followed by Propolis 15% and then the Calcium hydroxide when compared with the control group. Similarl results were seen for Heart rate where royal jelly 15% showed an increase in heart rate when compared to propolis 15% followed by Calcium hydroxide. Conclusion: Royal jelly and Propolis performed better than contemporary pulp capping agents.Survival rate , hatching rate as well as heart rate was higher for Apiarian products compared to Contemporary pulp capping agents.