Introduction: Oral cancer (OC) continues to be a major global health concern, marked by a high mortality rate, despite its largely preventable nature. This cross-sectional study sought to assess the current levels of knowledge, awareness, and behavioral patterns among patients from Out Patient Depatment concerning the danger signs connected to Oral Cancer. Methods: We conducted an anonymous survey consisting of 20 questions, which given to patients in the Dharmsinh Desai University, Nadiad, Faculty of Dental Science waiting areas. The survey responses were subjected to descriptive statistical analysis, and odds ratios pertaining to health literacy regarding Oral Cancer utilizing unconditional univariate logistic regression analysis, risk variables were determined. Results: 500 dental patients took part in the survey. The demographic analysis indicated that 62.2% of the participants were female. Furthermore, 41% of the entire participant pool had achieved a high school diploma or its equivalent as their highest educational attainment. Significantly, 34% of the participants disclosed current tobacco use or the consumption of smokeless tobacco, whereas 39% had a background of tobacco exposure. Furthermore, 54% of respondents acknowledged tobacco consumption, with varying frequencies : Infrequently (35%), 1-2 times per week (16%), 3-4 times per week (6%), 5-6 times per week (2%), and daily (23%). Additionally, approximately 50% of respondents demonstrated awareness of symptomatology associated with cancer. Notably, 20% of the survey participants reported tobacco cessation. Conclusion: Our results revealed that individuals consuming over 20 cigarettes daily demonstrated a greater awareness of the correlation between tobacco usage and the risk of OC (Oral Cancer), in contrast to non-smokers and those with a daily cigarette intake of 19 or fewer (p = 0.0647). Likewise, individuals who engaged in alcohol consumption exhibited heightened awareness of the increased risk of oral cancer associated with tobacco exposure. In summary, our research indicates that although patients acknowledged the correlation between tobacco use and oral cancer risk, there is potential for enhancing knowledge concerning additional contributing factors. Consequently, targeted education initiatives led by healthcare providers could significantly contribute to improving awareness of oral cancer risk factors.