Objective: The objective of this study was to assess the level of job satisfaction among medical sales personals working in state of Rajasthan of India Methods: This was a cross-sectional, survey based study. The study was conducted among medical personals working in different pharmaceutical in the state of Rajasthan in three stages as qualitative study, Pilot survey and Descriptive survey. A total of 149 respondents were considered in this study which include 49 response of Pilot survey and 100 response of Descriptive survey. The modified Likert Scale of (agreeability) questionnaire containing 20 questions was used for data collection. Both descriptive and inferential statistics were used for data collection and level of significance was used for data analysis. Results: Job satisfaction was rated as satisfactory among medical personals with a special focus on management policies, payment and other benefits, work profile, communication with management, working skill enhancement, management supervision and support, working condition and facilities and relation with colleagues were identified as factors leading to dissatisfaction. Age, education, company, position and experience were significantly associated with the study questions. Conclusion: It is concluded that the medical personals were encountered by several tasks in their duty. A number of issues disturb their capability to complete their responsibilities. Major concerns were related to management policies and deficiencies of job profile, lack of job security were identified as factors leading to dissatisfaction. In s