Background: Dental implants have emerged as the favored option for replacing teeth that are missing. Aim and objectives: To compare clinically, radiographically, and biochemically the crestal and subcrestal positioning of dental implants, Patients and methods: This randomized controlled clinical investigation has been performed on twenty systemically healthy cases of both sexes (10 men and 10 women) varying in age from twenty to fifty-five years. The cases included in the study have been chosen only from those who visited the outpatient's clinic at the Oral Medicine and Periodontology Department of the Faculty of Dental Medicine at Al-Azhar University, Assiut Branch. All chosen cases with partial edentulous maxillary anterior and premolar areas assessed by clinical and radiographic examination and indicated for delayed dental implant placement,