All kinds of life are seriously threatened by heavy metal contamination because of the negative consequences of long-term environmental degradation. The primary cause of water pollution is the discharge of industrial wastewater with high temperatures, supporting the sustainability of thermophilic bacteria. This study aimed to investigate the bioremediation potential of thermophilic bacteria isolated from Vajreshwari hot spring in Thane district, Maharashtra, India, against heavy metals Pb, Cr, As, and Cd. The identified bacteria— Pseudoxanthomonas taiwanensis strain (NFC7-A), Anoxybacillus salavatliensis strain (Y3MT21), and Bacillus licheniformis strain (HAZ6-17)—were subjected to heavy metal treatment individually, immobilized, and in consortium. The zone of inhibition was studied to screen for bioremediation potential, revealing that these bacteria could sustain up to 1000 ppm concentration individually for studied heavy metals, except Cd. However, immobilized cells and consortium proved to be the most effective. Notably, this study is the first report on these three bacterial species in the given area and their screening for immobilized as well as consortium applications, suggesting their potential use in bioremediation of Banganga river which is polluted with industrial wastewater polluted with toxic heavy metals.