Background: Anemia is a prevalent condition in pregnancy, posing significant risks to both maternal and neonatal health. This study investigates the relationship between anemia, coagulation parameters, and the incidence of postpartum hemorrhage (PPH) during childbirth. Methodology: A study design was cross-sectional study was carried out on 121 pregnant women attending the obstetrics department of Health Net Hospital, Peshawar, from January 2022 to January 2023.Blood samples were collected to evaluate hemoglobin levels and coagulation parameters, including prothrombin time (PT) and activated partial thromboplastin time (APTT). Data on postpartum hemorrhage was collected from medical records. Results: Of the 121 participants, 36 (29.8%) were anemic. A significant association was found between anemia and prolonged PT/APTT. Women with anemia had a 38% higher risk of experiencing postpartum hemorrhage compared to non-anemic women (p < 0.05). Conclusion: The findings highlight a significant link between anemia and coagulation abnormalities during pregnancy, emphasizing the need for effective management of anemia to mitigate the risk of postpartum hemorrhage.