Background: Diabetes mellitus (DM) is one of the main chronic health conditions of the 21st century.DM is a worldwide health problem, afflicting millions in both developed and developing countries between the worldwide population, 425 million people and 352.1 million people are estimated to have diabetes and impaired tolerance test for glucose, respectively. DM is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion and insulin action or both. Midway between normal glucose levels and diabetes diagnostic levels is pre-diabetes, also known as impaired glucose in fasting.