Objective: To assess and elucidate the phytochemical constituents of methanol extract of Phragmanthera capitata leaves (PCE) and the effect on depressive-like behaviour in using experimental rats. Methods: The PCE was obtained using cold marceration with methanol. The crude extract subsequently, was subjected to a comprehensive analysis involving thin-layer chromatography (TLC) and GC-MS techniques to identify its phytochemical constituents. Wistar rats were randomized into 5 groups of 5 rats each. Group I (negative control) received 10 ml/kg of 10% DMSO, Group II (standard) received 30 mg/kg imipramine hydrochloride, and Groups IV-VI (test) received 200, 400 and 800 mg/kg PCE respectively. Unprecedented Chronic Mild Stress (CMS) was induced every day for four consecutive weeks except Group I (control) and body weight was taken regularly. At the end of each stressor session, each rat was returned to the home cage and maintained in standard conditions till the next stress exercise. At the end of induction, the following tests were performed: Sucrose Preference Test (SPT) to assess anhedonia, Tail suspension test (TST) and Forced swimming test (FST) to assess behavioural despair.