Background: Axial Spondyloarthropathy (AxSpA) is a chronic inflammatory disease that affects axial skeleton (spine and sacroiliac joint) mainly causing severe pain and disability. It also affects peripheral joints and enthesis and can be assosciated with extra-articular manifestations as uveitis, psoriasis, and inflammatory bowel. Chronic back pain is the main clinical symptom of AxSpA and is usually the early clinical symptom. Back pain in AxSpA is usually of inflammatory character (Insidious onset, morning stiffness more than 30 minutes, improvement of back pain with movement and increase with rest, pain at night causing patient to awake during sleep, and alternating buttock pain. As an inflammatory autoimmune disease, AxSpA causes complications in many organ systems and tissues throughout the body including aortic regurgitation, pulmonary fibrosis, cauda Equina syndrome, mood disorders, chronic pain, aortic affection, osteoporosis, and Disability. Physiotherapy is an essential part of the treatment of AxSpA. It aims to alleviate pain, increase spinal mobility and functional capacity, reduce morning stiffness, correct postural deformities, increase mobility and improve the psychosocial status of the patients. Physical therapy components, like stretching exercises, posture education, range of motion exercises, strengthening exercises, Aerobic exercise, developing a plan for activity, movement, and posture that will preserve mobility and even strategies such as selecting the right mattress and workplace chair help to improve quality of life. AxSpA is a chronic condition for which there is currently no cure. The aim of treatment is essentially symptomatic with good control of symptoms, maintenance of function (facilitated by early diagnosis) and management of complications. Refer all new or suspected cases of AxSpA to a rheumatologist. This is for confirmation of the diagnosis, review of current treatment, access to specialist physiotherapy and occupational therapy and the arrangement of follow-up (often as part of a shared care arrangement with primary care). Treatment of extra-articular manifestations may require the involvement of other specialist teams. In this review we tried to givae a brief account about AxSpA diagnosis, and management.