Backgrounds: Due to the global spread of COVID-19 in 2020, there was a significant decrease in medical service utilization, and the perception of medical consumers towards medical institutions has been influenced by changes in the social environment. Therefore, we investigated the changes in safety awareness of medical service utilization among healthcare consumers in response to the COVID-19 pandemic. Purpose: The purpose of this study is to use the latest trends in safety awareness of medical utilization as a foundational data for patient safety education and safety activities among medical consumers at each medical institution. Methods: This study used the data of Medical Service Experience Survey in Korea. To compare before and after the outbreak of COVID-19, we collected and analyzed data from 2019 and 2021. The data were obtained through stratified random sampling, and the analysis included 12,507 and 13,546 participants in 2019 and 2021 respectively. Results: First, for both outpatient and inpatient services, the percentage of subjects who felt anxious for infection after the onset of COVID-19 was higher than before, with outpatient services showing 7.456 times higher and inpatient services showing 4.409 times higher anxiety. Second, with regard to safety facilities such as emergency exits and fire extinguishers in medical institutions, compared to before the outbreak of COVID-19, the rate of safety facility confirmation after the outbreak was 1.143 times higher in outpatient services, while there was no statistically significant difference in inpatient services.