Background: Periodontal therapy aims to eliminate the etiological factorswhich plays a primary role in the initiation and progression of disease. Photodynamic therapy is an advanced technique which involves three components; photosensitizer agent (Indocyanine green dye), source of light (LASER) and oxygen. Aim: To compare the efficacy of surgical periodontal therapy with PDT versus surgical periodontal therapy alone. Materials And Methods: 5 participants with Stage II or III, with Grade B or C periodontitis with PPD ≥5 mm on mandibular anterior teeth, were randomly assigned to surgical periodontal therapy (Group 1) and photodynamic therapy assisted surgery (Group 2). PI, GI, PPD, and CAL were measured using UNC-15 probe at baseline and 3months. Results: The intra group comparison of all the clinical parameters between 2 study groups were found to be non-significant. Only the intra group comparison of mean GI scores were found to be statistically significant in PTAS group. The inter gp comparison of all the clinical parameters at baseline and after 3 months were found to be significant for PTAS group.