Background: Video laryngoscopes have gained popularity for endotracheal intubation due to their improved visualization of the glottis. This study compared the performance of the BPL video laryngoscope and the TA scope in adult patients. Methods: In this randomized controlled study, 120 adult patients undergoing general anesthesia with endotracheal intubation were allocated to either the BPL group (n=60) or the TAS group (n=60). The primary outcome was the time to intubation (TTI). Secondary outcomes included first-attempt success rate, optimization maneuvers, hemodynamic parameters, and intubation complications. Results: The first-attempt success rate was similar between the BPL and TAS groups (86.66% vs. 91.61%, p=0.52). The TTI was significantly shorter in the BPL group (45.66±7.32 vs. 57.7±9.57 seconds, p<0.05). The TAS group required fewer optimization maneuvers (16.66% vs. 25%, p<0.05) and had higher hemodynamic changes (SBP, DBP, and pulse rate) after intubation. The incidence of intubation complications was comparable between the two groups. Conclusion: Both the BPL video laryngoscope and the TA scope are effective and safe for endotracheal intubation in adult patients. The BPL scope had a shorter TTI, while the TAS scope required fewer optimization maneuvers and resulted in higher hemodynamic changes. The choice between these devices should be based on patient factors, operator experience, and institutional resources.