Background; There is growing evidence that excess generation of highly reactive free radicals, largely due to hyperglycemia causes oxidative stress, which further exacerbates the development and progression of type 2 diabetes and its complications. Objective; Correlation between Glycated Hb and Non Conventional Parameter of Oxidative Stress. Material and Methods; This cross sectional study was carried out in the Department of Biochemistry, Government Medical College & Guru Nanak Dev Hospital Amritsar. Of the 200 subjects, 100 were type 2 diabetic patients and 100 were healthy non-diabetic individuals. Healthy non-diabetic individuals serve as controls for this study and were selected from the general population who visited the hospital's outpatient department. Results; Linear regression analysis showed a Positive Correlation between HbA1c and fasting blood glucose (r=0.417, p=0.000) with glycated Hb in patients with type 2 diabetes mellitus. Whereas negative correlation was observed between HbA1c with Non Conventional parameters, Ascorbic acid (r= 0.096, p=0.342), Uric acid (r= 0.025, p= 0.803), protein (r= 0.340, p=0.000), Albumin (r= -0.164, p=0.103), bilirubin (r= 0.069, p=0.494). Conclusions; The study concludes that type 2 diabetes is associated with oxidative stress, evidenced by altered levels of non-conventional oxidative stress markers. Lower levels of antioxidants and proteins in diabetics suggest increased oxidative damage, which may contribute to the progression of diabetic complications..