Volume 8 | Issue - 8
Volume 8 | Issue - 8
Volume 8 | Issue - 7
Volume 8 | Issue - 7
Volume 8 | Issue - 6
Background: Although pulmonary TB is more common, neuro-tuberculosis is the more severe form of tuberculosis, causing death or major neurological sequelae in children despite of treatment Aim: The primary objective of this study is socio-demographic and clinical evaluation of neuro-tuberculosis children and its correlation with the BCG vaccination Materials and methods: Total 45 cconfirmed tuberculosis Children of 6 months-12 years of age presenting with neurological manifestations were enrolled in this study. Detailed socio-demographic history, presenting symptoms, neurological examination and BCG immunization status of the child was documented. All relevant investigation was done in each recruited subject Results: Majority of the children (85.7%) belonged to >5 years of age, predominantly males. No significant association was shown between BCG vaccination and demographic variables (p>0.05). Meningeal irritation and abnormal movements were most common clinical signs of neuro-tuberculosis among BCG vaccinated children and half of them had tubercular meningitis stage 1. HIV status was positive in significantly higher proportion of children with no BCG scar (P<0.05). However, no significant association of BCG scar with Mantoux test and BCG vaccination and mortality in neuro tuberculosis children (p>0.05). Conclusion: Identifying and managing factors responsible for neuro tuberculosis can prevent morbidity and mortality associated with the neuro tuberculosis in children