The cross-semantic analysis of business terms in English and Uzbek languages aims to uncover the linguistic and cultural nuances that shape business communication in these languages. By examining terms from various business sectors such as finance, marketing, management, and entrepreneurship, this study identifies both direct translations and culturally influenced adaptations. The research highlights the importance of metaphorical language and the impact of globalization on the Uzbek business lexicon. The findings underscore the significance of cultural competence in international business, offering valuable insights for linguists, translators, and business professionals navigating bilingual environments.