Obesity increases the risk of cardiovascular disease due to associated dyslipidaemia, type 2 diabetes, hypertension, and sleep disorders. Independent to other cardiovascular risk factors, obesity leads to increase in morbidity and mortality related to the cardiovascular disease. In the present study, knowledge regarding prevention of cardiovascular disease among 100 obese adults was assessed in Sangli, Miraj and Kupwad corporation area. A descriptive study design was planned. Non- probability, convenient sampling technique was adopted to recruit total of 100 subjects. A structured knowledge questionnaire was used to collect the data. A detail evaluation of different domains of knowledge regarding prevention of cardiovascular disease was assessed. The weak knowledge domains were identified. Based on the findings, an educational booklet was developed, targeting to improve the knowledge in weak domains. The booklet was distributed among the obese adults in the community to enhance the knowledge of the obese adults about prevention of cardiovascular disease.