Background: Background: Cholangiocarcinoma is the second most frequent type of liver cancer after hepatocellular carcinoma. It is a moderately common liver cancer. The multidetector CT (MDCT) is a noninvasive imaging modality of choice, which is used to evaluate patients in order to determine the location of the obstruction, identify distant metastases, and determine mass lesions. Aim of the study: The purpose of this research is to determine how the MDCT scan contributes to the visualization of cholangiocarcinoma imaging findings, their classifications, and the preoperative assessment that is crucial for the disease's diagnosis and staging. Patients and Methods: Our present study included 50 patients with biliary obstruction and previously radiological or laboratory diagnosed cases of cholangiocainoma after obtaining written informed consent, meeting the inclusion and exclusion requirements. Results: They had a mean age of 63.1± 10.2 years. Males outnumbered females and accounted for 56% versus 44% of females. In correlation to histopathological findings, MDCT was 96% sensitive in detection of cholangiocarcinoma. A statistically significant correlation was observed between the site, type, and TNM staging. As CBD and hilar cholangiocarcinoma were mostly early stages (II, and III), while peripheral type was associated with advanced staging mainly stage IV, followed by stage II and stage III with p value 0.001. High significant association was detected between site, type and vascular invasion, as CBD and hilar cholangiocarcinoma were not associated with vascular invasion, while peripheral type was associated with invasion of portal vein mainly, followed by hepatic artery and finally hepatic vein with p value 0.012. Conclusion: Multidetector computed tomography MDCT can be considered a noninvasive , fast and high sensitivity imaging tool in the assessment of patients with cholangiocarcinoma for accurate staging and preoperative assessment of the tumor extent..