Dental caries is a dynamic process characterized by alternating cycles of demineralization and remineralization, influenced by factors such as bacterial activity, dietary habits, and salivary composition. Current caries management focuses on early detection of carious lesions and enhancing remineralization to restore lost minerals and prevent lesion progression. Bioactive glass has emerged as a promising material for enamel remineralization, offering an effective alternative to conventional fluoride-based treatments. Its unique ability to release calcium and phosphate ions facilitates hydroxyapatite formation, enhancing enamel integrity and resistance to demineralization. This narrative review explores the role of bioactive glass in the management of white spot lesions, highlighting its mechanism of action and various delivery systems, including toothpaste, varnishes, air abrasion powders, bleaching agents, and orthodontic adhesives.