Introduction:Odontogenic infection in diabetic patients has always been a challenge for the treating maxillofacial surgeons. Thus the aim of this study is to evaluate any seasonal variation which affects the spread of odontogenic infection in diabetic patients. Material and methods: A retrospective epidemiological study was done by obtaining record from October 2014 to September 2021 were and analysed. 597 patients.Clinical features studied were demography (age, sex), spaces involved, systemic diseases, presentation upon hospital admission (symptoms and signs, temperature), duration of hospital stay, and complications. Results: Odontogenic infection was more frequently observed in summers than other season and diabetic patients are more prone to get infection in summers (47.7%). Mandiblular space infection were more frequently seenrather than maxillary infection. The length of hospital stay and complication observed in diabetic patient is more than nondiabetic group. Conclusion: In summer season the diabetic patients are more prone to maxillofacial infection.