A field trial was conducted at Jawahar Model Farm, JNKVV, Jabalpur, from June 2022 to June 2023 to assess the impact of insecticides on lac insect survival across six Cajanus cajan landraces. Using a Split Plot Design, the trial evaluated three treatments: chlorantraniliprole followed by emamectin benzoate, emamectin benzoate followed by emamectin benzoate and a control (water spray), revealing significant differences in insect survival based on insecticide use and landrace variation. This study investigates the impact of different insecticide combinations on mean number of live lac insect (MNL) of Cajanus cajan across multiple time points: 30th, 60th, 90th, 120th, 150th, and 180th days after brood lac inoculation (BLI). Results show that chlorantraniliprole followed by emamectin benzoate (M1) consistently achieved the highest MNL values and significantly reduced lac insect losses compared to emamectin benzoate alone (M2) and water spray (M3). On the 30th day post-BLI, MNL ranged from 161.89 (M1S4) to 178.11 (M3S5), with M3 + S5 producing the highest MNL. At 60 days, MNL was highest with M1S1 (175.72), followed closely by M3S5 (168.46), and M1 also resulted in the lowest lac insect loss (1.10%). By 90 days, predator activity had increased, leading to MNL losses peaking at 22.52% with the control (M3). Chlorantraniliprole (M1) and emamectin benzoate (M2) treatments reduced this loss to 14.06% and 14.37%, respectively. The MNL trends continued at 120, 150, and 180 days, with the M1 + S1 and M1 + S5 combinations consistently outperforming other treatments. At 180 days, MNL declines were lowest in treated landraces, highlighting the critical role of insecticides in protecting lac insects from natural enemies and minimizing economic losses.