On paper, processes, and anti-doping institutions in India are similar to majority of jurisdictions in the world. However, there are some differences in the procedure of implementation of various aspects of the code comprising respect to education, testing, and other procedural elements that lead to such consequences that damage the career and lives of an athlete. DNA testing is a potential approach that can reduce the risk of such unwanted consequences in sports in the country. There are several limitations that can limit effectiveness of DNA testing in anti-doping protocols. However, better identification of the issues will help in planning and implementation of interventions to address the concerns and effective incorporation of the standard in the anti-doping protocol. DNA testing will help safeguard the athlete’s rights and ensure fair play. Legal framework and policy will be implemented in a manner that privacy, confidentiality, and informed consent in DNA testing will be maintained. In addition, all members will comply with guidelines to reduce the risk of misuse and errors. Doping is harmful and deceptive to athletes. However, false allegation hampers quality of life of an athlete to a higher extent. Thus. Effective anti-doping regulations are important to ensure safety and clean and fair sport.