Plants have been one of the important sources of medicines since the beginning of human civilization. Artocarpus Heterophyllus Linn. Belonging to family Moraceae, commonly found in India. The plant is used as anaemia, asthma, dermatitis, expectorant etc. The antihyperlipidemic activity of alcoholic extract of bark of Artocarpus Heterophyllus was evaluated using high–cholesterol diet model and triton-induced hyperlipidemia model in Wistar rats. In this model, five groups (six animals per group) of animals were used. Group I-served as normal control and were given only vehicle (distilled water); Group II- received high fat diet served as hyperlipedemic control; Group III-received atorvastatin 10 mg/kg served as standard drug; Group IV-received 200 mg/kg AAHP andGroupV-received 400mg/kg of AAHP. Serum cholesterol and triglycerides (TGs) level are estimated for the evaluation of antihyperlipidemic effects of extracts. The ethanolic extract has shown a significant reduction in serum cholesterol and TGs level indicating antihyperlipidemic potentials in the plant. In this high–cholesterol diet model and triton-induced hyperlipidemia model, serum and TG levels were analyzed ethanolic extract was shown antihyperlipidemic activity. Further clinical studies are compulsory to confirm the findings.