Objective: To examine the relationship between serum uric acid and the presence and severity of diabetic peripheral neuropathy in patients with type 2 diabetes." Methodology: This prospective cohort study was conducted in Central Park Medical College and Teaching Hospital Lahore from June 2024 to December 2024 on 300 subjects after random collection following the principles outlined in the Declaration of Helsinki and was approved by the Institutional Review Board (IRB# CPMC/IRB-No/1415) of Central Park Medical College and Teaching Hospital. Verbal informed consent was obtained from all participants before inclusion in the study, and patient confidentiality was maintained throughout the study. The sample size was calculated using open epi software based. A clinical study was conducted on DNP patients with high levels of uric acid A control and experiment group was made of 30 each of ages ranging from 20-45 excluding patients having gout, renal dysfunction, acute illness, surgery, and pregnancy. Results: Baseline Characteristics: There were no significant differences in age (54 ± 7.4 vs. 55 ± 7.9 years), duration of diabetes (10 ± 3.3 vs. 8 ± 3.0 years), HbA1c levels (8.1 ± 1.4 vs. 7.8 ± 1.3%), and BMI (28.5 ± 4.1 vs. 28.7 ± 2.8) between the DPN and control groups (p > 0.05 for all). Serum Uric Acid Levels: The DPN group exhibited significantly higher serum uric acid levels (5.7 ± 1.0 mg/dl) compared to the control group (4.3 ± 0.9 mg/dl) (p = 0.02), indicating an association with diabetic peripheral neuropathy. Correlation with Neuropathy Scores: There were positive correlations between serum uric acid levels and neuropathy scores, with correlation coefficients of 0.34 (p = 0.01) for MNSI, 0.40 (p = 0.01) for NDS, and 0.30 (p = 0.04) for VPT, suggesting that higher uric acid levels are linked to increased neuropathy severity Conclusion: This study demonstrates that while baseline characteristics between the DPN and control groups were similar, the DPN group had significantly elevated serum uric acid levels, suggesting a potential link to diabetic peripheral neuropathy. Furthermore, positive correlations were observed between serum uric acid levels and neuropathy severity scores. These findings highlight the importance of monitoring serum uric acid in diabetic patients to identify those at risk for neuropathic complications.