ISSN : 2663-2187

Fetomaternal Outcomes in Women with Hyperemesis Gravidarum in the First Trimester: A Retrospective Study

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Neelum zahir, Kiran kalsoom, Nazia Sayed, Asma Hameed, Maryam afridi, sadaf Ali
» doi: 10.48047/AFJBS.4.4.2022.249-256

Abstract

Background: HG is a form of pregnancy sickness whereby pregnant women experience severe nausea and vomiting, failure of which leads to dehydration, weight loss and other complications of electrolyte imbalances. This condition affects 0. 5% to 2% of pregnancies, thus implicating high dangers to the mother and the fetus when it occurs in the first trimester. Objectives: To evaluate the place of sufficiently proved diagnosis of hyperemesis gravidarum at the first trimester of pregnancy in relation to the outcome for both the mother and the fetus. Study design : A retrospective study.Duration and place of study. Department of gyne saidu group of teaching hospital , swat from jan 2021 to july 2021Methods : The present Retrospective Study 100 first-trimester hyperemesis gravidarum women who had received treatment . In this study maternal age, gestational weeks, pre-pregnancy BMI, symptom severity, hospitalization length, and neonatal data were assessed and evaluated. Results : In the present sample of one hundred women diagnosed with hyperemesis gravidarum during the first trimester, the mean maternal age was 28. 4+4. 6 years. The mean age of diagnosis was 9. 2 weeks of gestation, standard deviation 1. 8 weeks. About 68% of the patients needed to be hospitalized, they spent on average of 5. 7 days (SD = 2. 3) in the hospital. Moderate maternal weight loss could be seen in the study, 4. 2 kg (SD = 1. 5 kg) on an average. Abnormal levels of electrolytes were detected in 32 per cent of the episodes. The mean birth weight was 2,870 grams (SD = 410 grams), and 410 grams 18% neonates were SGA. Preterm delivery has been noted at a rate 12% and 14% of born neonates were admitted in NICU. Hyperemesis gravidarum and SGA had significant relationship in the study and the p- value was 0. 03. When comparing the results of the association between HG and preterm delivery, the authors obtained a p-value of 0. 07; thus, an association exists but does not precisely reach the level of statistical significance. Conclusion First-trimester HG has been associated with adverse maternal and fetal effects, including serious maternal complications and raised odds of restricted fetal growth and preterm birth. There is a definite need to make an early diagnosis and provide individualised management to such patients.

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