The guava leaves are obtaining from the plant Psidium guajava l belongs in to family Mrytaceae. Guava leaves have long been used effectively due to their antimicrobial, antibacterial and antiulcerproperties .There are several type of jellies are available to treat ulcre like medicated jellies , lubricant jellies, miscellaneous jellies. The aim for this research is prepared a oral medicated jellies with the help of guava leaves for the treatment of peptic ulcer .The oral route of administration is the most convenient and acceptable route for the patient compliance and acceptance