ISSN : 2663-2187

Formulation Development & Evaluation Of Mouth Dissolving Tablet Of Torsemide

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Mohd. Faarooq Khan, Dishant Gupta, Sudha Vengurlekar, Sachin Kumar Jain
ยป doi: 10.33472/AFJBS.6.1.2024.258-271


The oral route of medication delivery is the most popular and generally recognized. Oral dose forms are often used due to their cost-effectiveness and convenience of self-administration. For example, mouth dissolving tablets dissolve in saliva and may be eaten without the need for water. The pre-compression characteristics of a powder blend, weight variation test, thickness test, hardness, friability, drug content, wetting time, water absorption ratio, and disintegration time were used to evaluate the tablets. Torsemide is indicated for the treatment of oedema associated with congestive heart failure, renal, or hepatic diseases. This research is designed for fast release of drug for treatment of oedema. The tablet was prepared by Torsemide (Solid Dispersion), Crospovidone, Sodium starch glycocolate, Mannitol, Magnesium Stearate, Talc, and Aspartame in eight different batches (T1-T8 formulations).As a consequence, it was noted that the T7 formulation outperformed the others in terms of disintegration time, water absorption ratio, and wetting time.

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